The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Hypersensitivity ... • Ex: Systemic Lupus ... #Allergy #Allergic ... Reactions #Types #Classification ... #Diagnosis #Definitions
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... clinical findings Definition ... leading to an allergic ... Sensitization" to Allergen ... Anaphylaxis #TypeI
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
Type III Hypersensitivity ... clinical findings Definition ... : • Systemic Lupus ... Serum sickness #TypeIII ... HypersensitivityReaction #Allergy
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... clinical findings Definition ... mediated; exposure to allergen ... Allergic reaction ... Poison ivy) #TypeIV
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Hypersensitivity ... : Definitions ... #Hypersensitivity ... Reactions #Types #Classification ... #Diagnosis #Definitions