The Calgary Guide to Understanding Disease @TheCalgaryGuide
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allergy immunology pathophysiology classification diagnosis hypersensitivity reactions type1 type2 type3 type4 typei typeiii typeiv types
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
clinical findings Definition ... leading to an allergic ... Sensitization" to Allergen ... Initial exposure to allergen ... #TypeI #Type1 #HypersensitivityReaction
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... Ex: Antibiotic allergies ... fever, Urticaria, Allergic ... • Ex: Systemic Lupus ... Classification #Diagnosis #Definitions
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
clinical findings Definition ... mediated; exposure to allergen ... Allergic reaction ... TypeIV #Type4 #HypersensitivityReaction ... #Allergy #Immunology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
clinical findings Definition ... : • Systemic Lupus ... TypeIII #Type3 #HypersensitivityReaction ... #Allergy #Immunology
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
clinical findings Definition ... #Type2 #Type2 #HypersensitivityReaction ... #Allergy #Immunology
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