The Calgary Guide to Understanding Disease @TheCalgaryGuide
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allergy hypersensitivityreaction immunology pathophysiology classification diagnosis hypersensitivity types type1 type2 type3 type4 typei typeiii typeiv
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Penicillin-induced drug reaction ... • Ex: Systemic Lupus ... Dermatitis (ie. reaction ... #Allergic #Reactions ... Classification #Diagnosis #Definitions
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
clinical findings Definition ... leading to an allergic ... reaction. ... Sensitization" to Allergen ... Initial exposure to allergen
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
Hypersensitivity: Definitions ... reaction • Type ... An allergic reaction ... #Allergic #Reactions ... Classification #Diagnosis #Definitions
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
clinical findings Definition ... mediated; exposure to allergen ... development of allergen-specific ... Allergic reaction ... Initial exposure to allergen
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
clinical findings Definition ... : • Systemic Lupus ... HypersensitivityReaction #Allergy
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
clinical findings Definition ... antibody-mediated immune reaction ... HypersensitivityReaction #Allergy
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