Ravi Singh K @rav7ks
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Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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diagnosis differential management aids cardiology hematology hiv rheumatology erythematosus fungal leukemia lupus macrophage mycoses neurology opportunistic pulmonary syndrome systemic
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
CNS Infection in ... from reactivation ... Antimicrobial treatment ... diameter - +mass ... opportunistic #InfectiousDiseases
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
fibromyalgia) • Infections ... CNS • Headache ... • Libman-Sacks endocarditis ... lymphopenia, low PLT • Anemia ... Chronic B-cell activation
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Infectious: • Pre-existing ... verrucous) • Lung ... • Autoimmune (SLE ... occlusion that may ... Leukocytosis, anemia
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
nervous system (CNS ... rash) • Heart, lung ... erythematosus [SLE ... ], AOSD) • Infection ... with leukopenia, anemia
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Lymphadenopathy, CNS ... 100% of cases), anemia ... #Infections #HIV ... differential #diagnosis #infectiousdiseases
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL: mediastinal mass ... involvement • 30%: CNS ... leukostasis syndrome: CNS ... - infiltrates (anemia ... Leukemia #Hematology #Oncology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
, verrucous) - Lung ... • Autoimmune (SLE ... Leukocytosis, anemia ... hematuria, + RF Treatment ... Diagnosis #cardiology #infectiousdiseases
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
especially the CNS ... MC: CNS CSF: • ... change in the lungs ... arthritis, and endocarditis ... ) #Mycoses #InfectiousDiseases
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