Ravi Singh K @rav7ks
1.1M 733 353
Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Endogenous reactivation ... of a latent infection ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
• Endogenous reactivation ... of a latent infection ... Tuberculosis Treatment ... Initiating Treatment ... Diagnosis #Management #Treatment
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... result from reactivation ... of latent pathogens ... Antimicrobial treatment ... opportunistic #InfectiousDiseases
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Histoplasmosis Treatment ... change in the lungs ... arthritis, and endocarditis ... nails, bronchi, lungs ... ) #Mycoses #InfectiousDiseases
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... rash) • Heart, lung ... SLE], AOSD) • Infection ... with leukopenia, anemia ... Treatment: • Corticosteroids
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Infectious: • Pre-existing ... , verrucous) - Lung ... Leukocytosis, anemia ... hematuria, + RF Treatment ... Diagnosis #cardiology #infectiousdiseases
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
fibromyalgia) • Infections ... • Libman-Sacks endocarditis ... lymphopenia, low PLT • Anemia ... Chronic B-cell activation ... and leukemia • Lung