Ravi Singh K @rav7ks
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Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate Dehydrogenase ... Prosthetic valves Lung ... pneumonia (late) • Tuberculosis ... Pneumonia • Other lung ... • Toxins • Infection
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacterium tuberculosis ... infections • ... Bone Marrow - Anemia ... patients with typical tuberculosis ... differential #diagnosis #infectiousdiseases
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... Mycobacterium tuberculosis ... 100% of cases), anemia ... #Infections #HIV ... differential #diagnosis #infectiousdiseases
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
rash) • Heart, lung ... SLE], AOSD) • Infection ... with leukopenia, anemia ... Triglycerides • ↑ Lactate dehydrogenase ... Treatment: • Corticosteroids
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
, verrucous) - Lung ... Leukocytosis, anemia ... hematuria, + RF Treatment ... Differential #Diagnosis #cardiology ... #infectiousdiseases