Ravi Singh K @rav7ks
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Academic Hospitalist and Program Director @SinaiBmoreIMRes, Medicine clerkship director GW School of Medicine and Health Sciences RMC at Sinai, Clinical reasoning,Simulation and POCUS enthusiast - https://twitter.com/rav7ks
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Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
infections/year ... mycobacterial infection ... Treatment: Active ... Initiating Treatment ... Diagnosis #Management #Treatment
Tuberculosis Testing

LATENT TB
• LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
developing active infection ... infection • Recent ... viral infections ... Extrapulmonary infection ... LatentTB #ActiveTB #InfectiousDiseases
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
infections/year ... mycobacterial infection ... Treatment: Active ... Initiating Treatment ... Diagnosis #Management #Treatment
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... Antimicrobial treatment ... 80% sensitive Tuberculous ... - Hemorrhage, tuberculomas ... opportunistic #InfectiousDiseases
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
., HIV), EBV infection ... Etiology: - Infections ... Solid Tumors • Tuberculosis ... NonHodgkins #comparison #oncology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
diagnosis and treatment ... Non-inflammatory causes: • Infectious ... • Syphilis • Tuberculosis ... • Enteroviral infections ... • Herpes virus infections
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacteria (NTM) Infections ... Mycobacterium tuberculosis ... Factors For NTM Infections ... patients with typical tuberculosis ... differential #diagnosis #infectiousdiseases
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... Mycobacterium tuberculosis ... Extrapulmonary tuberculosis ... Microsporidium #Lung #Infections ... differential #diagnosis #infectiousdiseases
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Neutropenia - recurrent infections ... Idiopathic • Infections ... aplastic anemia Treatment ... Aplastic #Anemia #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... microglobulin Treatment ... diagnosis #workup #oncology