Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... hepatitis - Acute biliary ... Hemochromatosis - Primary biliary ... cholangitis ... Severe #Acute #Causes
Gallstone Diseases
1. Asymptomatic Stones 75%
2. Biliary Pain 20%
3. Acute Cholecystitis 10%
4. Mirizzi's Syndrome < 0.1%
5. Cholangitis/
Biliary Pain 20% ... Cholangitis/ Pancreatitis ... differential #diagnosis #causes
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... Benign/malignant biliary ... cholangitis, Primary ... sclerosing cholangitis
Algorithm for the Diagnosis of Primary Biliary Cholangitis (PBC). 

US, ultrasound; MRCP, magnetic resonance cholangiopancreatography; ALP,
Algorithm for the ... Diagnosis of Primary Biliary ... Cholangitis (PBC ... #Cholangitis #PBC ... #Algorithm #Diagnosis
Functional Dyspepsia - Pathophysiology, Diagnosis and Management
Risk factors: Non-steroidal anti-inflammatory drugs, Psychological comorbidity, Helicobacter pylori infection,
Functional Dyspepsia ... a structurally normal ... Early satiety #Functional ... Diagnosis #Management #algorithm
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... initial response to abnormal ... include extrahepatic biliary ... #Algorithm #Hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... <45% and SF is normal ... out additional causes ... If other causes ... hemochromatosis #algorithm
Rome IV Criteria for diagnosing Functional Abdominal Pain Disorders (FAPD)
Irritable bowel syndrome
The criteria must be fulfilled
for diagnosing Functional ... resolves have functional ... medical condition Functional ... interferes with normal ... following: anorexia, nausea