Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... biliary obstruction ... Hemochromatosis - Primary biliary ... cholangitis ... #Causes #Differential
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... cholangitis, Primary ... dechallenge • Acute ... Hepatic vascular disorder
Gallstone Diseases
1. Asymptomatic Stones 75%
2. Biliary Pain 20%
3. Acute Cholecystitis 10%
4. Mirizzi's Syndrome < 0.1%
5. Cholangitis/
Biliary Pain 20% ... Acute Cholecystitis ... Cholangitis/ Pancreatitis ... differential #diagnosis #causes
Functional Dyspepsia - Pathophysiology, Diagnosis and Management
Risk factors: Non-steroidal anti-inflammatory drugs, Psychological comorbidity, Helicobacter pylori infection,
Functional Dyspepsia ... pylori infection, Acute ... a structurally normal ... Early satiety #Functional ... Diagnosis #Management #algorithm
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... tests algorithm ... initial response to abnormal ... include extrahepatic biliary ... #Algorithm #Hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... <45% and SF is normal ... and hematologic disorders ... If other causes ... hemochromatosis #algorithm
Causes of a low fecal elastase
Abnormal pancreatic imaging:
Chronic pancreatitis, Pancreatic tumours including cystic disease, Pancreatic resection,
Causes of a low ... fecal elastase Abnormal ... Pancreatic atrophy, Acute ... pancreas), Genetic causes ... Rheumatological disorders
Rome IV Criteria for diagnosing Functional Abdominal Pain Disorders (FAPD)
Irritable bowel syndrome
The criteria must be fulfilled
Abdominal Pain Disorders ... episodes of intense, acute ... interferes with normal ... following: anorexia, nausea ... AbdominalPain #Disorders