Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... hepatitis - Acute biliary ... Hemochromatosis - Primary biliary ... cholangitis ... Severe #Acute #Causes
Gallstone Diseases
1. Asymptomatic Stones 75%
2. Biliary Pain 20%
3. Acute Cholecystitis 10%
4. Mirizzi's Syndrome < 0.1%
5. Cholangitis/
Biliary Pain 20% ... Cholangitis/ Pancreatitis ... differential #diagnosis #causes
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... Benign/malignant biliary ... cholangitis, Primary ... sclerosing cholangitis
Algorithm for the Diagnosis of Primary Biliary Cholangitis (PBC). 

US, ultrasound; MRCP, magnetic resonance cholangiopancreatography; ALP,
Algorithm for the ... Diagnosis of Primary Biliary ... Cholangitis (PBC ... #Cholangitis #PBC ... #Algorithm #Diagnosis
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
function tests algorithm ... indicate the initial evaluation ... include extrahepatic biliary ... #LFTs #Abnormal ... #Algorithm #Hepatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... normal, further evaluation ... C282Y homozygote, evaluation ... If other causes ... hemochromatosis #algorithm