Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... Hemochromatosis - Primary ... biliary cholangitis ... #Causes #Differential
Gallstone Diseases
1. Asymptomatic Stones 75%
2. Biliary Pain 20%
3. Acute Cholecystitis 10%
4. Mirizzi's Syndrome < 0.1%
5. Cholangitis/
Acute Cholecystitis ... Cholangitis/ Pancreatitis ... Gallstone #Diseases #differential ... #diagnosis #causes
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... biliary cholangitis ... , Primary sclerosing ... dechallenge • Acute
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... indicate the initial evaluation ... history alongside evaluation ... #Algorithm #Hepatology ... Liver #Enzymes #Differential
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... <45% and SF is normal ... , further evaluation ... C282Y homozygote, evaluation ... hemochromatosis #algorithm
Causes of a low fecal elastase
Abnormal pancreatic imaging:
Chronic pancreatitis, Pancreatic tumours including cystic disease, Pancreatic resection,
Causes of a low ... fecal elastase Abnormal ... Pancreatic atrophy, Acute ... elastase #low #differential ... #diagnosis #causes
Rome IV Criteria for diagnosing Functional Abdominal Pain Disorders (FAPD)
Irritable bowel syndrome
The criteria must be fulfilled
After appropriate evaluation ... After appropriate evaluation ... episodes of intense, acute ... interferes with normal ... following: anorexia, nausea