Dr. Michael Chew @mchew85
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GrepMed Gastroenterology-Hepatology Editor, Academic Hospitalist UC Davis Medical Center Internal Medicine, Yale Gastroenterology Fellow '22
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Table of Causes of Acute Liver Injury
#Diagnosis #Hepatology #Acute #Liver #Injury #Causes #Differential #Incidence #Table #Failure
Table of Causes ... #Diagnosis #Hepatology ... #Acute #Liver # ... Injury #Causes # ... Differential #Incidence
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... hepatitis - Acute ... #Causes #Differential ... #Hepatology #Diagnosis
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Drugs and Classes ... #Medications #Differential ... #LiverInjury #Hepatology ... #Pharmacology #Causes
An Approach to Jaundice - Differential Diagnosis

- Increased Production (Prehepatic)
- Decreased Clearance (Intrahepatic + Posthepatic)

Dr. Eric
to Jaundice - Differential ... #Jaundice #Differential ... #Table #Causes ... Posthepatic #Diagnosis #Hepatology
Gallstone Diseases
1. Asymptomatic Stones 75%
2. Biliary Pain 20%
3. Acute Cholecystitis 10%
4. Mirizzi's Syndrome < 0.1%
5. Cholangitis/
Acute Cholecystitis ... Gallstone #Diseases #differential ... #diagnosis #causes
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
#Diagnosis #Differential ... #Hepatology #Cirrhosis ... #Causes
Causes of Low Vitamin B12 Levels
Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people
Autoimmune
Causes of Low Vitamin ... B12 Levels Low ... VitaminB12 #deficiency #low ... #cobalamin #differential
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
-40 years • Low ... undetectable, low ... immunosuppression • Acute ... > 3 mg/dL) or acute ... Indications #management #hepatology
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
oncotic pressure Low ... liverprof #Diagnosis #Hepatology ... Interpretation #Differential
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
for alternative causes ... dechallenge • Acute ... Diagnosis #Algorithm #hepatology