2332 results
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... hyperglycemia in type 2 ... #Diabetes #Pathophysiology
Shock - Pathophysiology 
Inadequate tissue perfusion to meet O2, nutrient requirements
1. Distributive Shock
2. Hypovolemic Shock
3. Cardiogenic
Shock - Pathophysiology ... Distributive Shock 2. ... Shock #Shock #Pathophysiology
Diverticular Disease Pathophysiology
1) Diverticulosis
2) SUDD (Symptomatic Uncomplicated Diverticular Disease)
3) Diverticulitis
4) Diverticular bleeding

DOI: 10.1038/s41572-020-0153-5

#Diverticular #Disease #Pathophysiology #diverticula
Diverticular Disease Pathophysiology ... Diverticulosis 2) ... Diverticular #Disease #Pathophysiology
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... canagliflozin 2) ... Adenosine #Nephron #Pathophysiology
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
., IL-1, IL-2 Muromonab-CD3 ... synthesis - IL-2 ... Basiliximab - IL-2 ... Suppression of IL-2 ... #Pharmacology #Pathophysiology
The Cardiac Cycle Animated - Systole, Diastole, Pressures and Volume - (slowed down version @ 1/2
down version @ 1/2 ... speed) #Pathophysiology
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Wasting vs SIADH - Pathophysiology ... Neurological event 2) ... SaltWasting #SIADH #Pathophysiology
Renal Tubular Disorders

 • Distal Renal Tubular Acidosis (Type 1)
 • Proximal Renal Tubular Acidosis (Type
Acidosis (Type 2) ... Acidosis #Types #pathophysiology
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
nontoxic) or 2) ... Toxicity #Toxicology #Pathophysiology
Hypothermia in Sepsis - Pathophysiology
 • 20% of septic pts → HYPOTHERMIA
 • Increased mortality 62%
Hypothermia in Sepsis - Pathophysiology ... and heat loss 2. ... Hypothermia #sepsis #pathophysiology