3354 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... disomy: inheriting 2 ... =>Prader-Willi Syndrome ... Obesity -> Type 2 ... #genetics #pathophysiology
Management of Necrotizing Pancreatitis

Severe Pancreatitis
Pathophysiology
Diagnosis of Pancreatic Necrosis
Infected Necrosis
Complications of Severe Pancreatitis: 
1) Pancreatic Fistula
2) Disconnected
Pancreatitis Pathophysiology ... Pancreatic Fistula 2) ... Pancreatic Duct Syndrome
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
iniury, Compartment syndrome ... Neuroleptic malignant syndrome ... Dermatomyositis) AKI - Pathophysiology ... renal ischemia 2. ... Iinitial rate: 1-2
Peripheral Edema - Differential Diagnosis Framework for Lower Extremity Edema

Edema occurs when any of the following
hydrostatic pressure (2) ... • May-Thurner Syndrome ... regional pain syndrome ... • SVC syndrome ... #PhysicalExam #Pathophysiology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... post-sarcoidosis fatigue syndrome ... Specific sarcoidosis syndromes ... symptoms) • Löfgren syndrome ... • Heerfordt syndrome
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Epidemiology: • 1-2 ... Guillain-Barre Pathophysiology ... Miller Fisher Syndrome ... demyelination features (2)
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Presenilin 1 and 2 ... mutations - Down syndrome ... AlzheimersDisease #Dementia #pathophysiology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Stiff Person Syndrome ... Prevalence: 1-2 ... 20-50, Females 2- ... Pathophysiology ... anti-GAD (positive in 2/
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Encephalopathy Syndrome ... Etiology: • Pathophysiology ... : Acute onset 2. ... 105 mmHg within 2 ... correction: Levels 2-
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... common in APL (2- ... ATRA treatment Pathophysiology ... Moderate > 2/3 and ... Differentiation #Syndrome