73 results
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... 3. ... Signs / Symptoms ... #Anaphylaxis #pathophysiology ... immunology #diagnosis #signs
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... have fever - ACS ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
spontaneous within 3- ... 6 months of symptom ... MeralgiaParesthetica #MSK #pathophysiology ... differential #diagnosis #signs ... #symptoms
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Signs and symptoms ... Multiple Sclerosis Treatment ... 1000 mg daily 3- ... an oral taper 3- ... management #neurology #treatment
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Gaucher Disease Pathophsiology ... involvement (type 2 and 3) ... Disease #Diagnosis #Signs ... #Symptoms
Hypertonic Saline for Treatment of Hyponatremic Encephalopathy
1) 100 ml bolus of 3% NaCl over 10 min.
Hypertonic Saline for Treatment ... NaCl over 10 min ... Symptoms improve ... urine output for signs ... Hypertonic #Saline #Treatment
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
gene mutated in all ... Retinoblastoma Signs ... / Symptoms / Complications ... Retinoblastoma #pathophysiology ... #symptoms
Pemphigus Vulgaris vs Bullous Pemphigoid - Comparison Table
Pemphigus Vulgaris
 • Epidemiology: Average age 40-60
 • Time
, relapsing • Symptoms ... ruptured • Nikolsky sign ... desmoglein 1 and 3 ... , relapsing • Symptoms ... Tense • Nikolsky sign
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
When present, symptoms ... , signs, and complications ... • "Vasomotor" symptoms ... transformation into AML ... the reduction of symptoms
Management of Hyponatremia
Hypertonic Saline - Only indicated if patient has severe symptoms + Na < 125
Give
patient has severe symptoms ... (Max of 3 doses) ... -6 mmol/L over 3- ... give specific treatment ... Management #algorithm #treatment