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diagnosis management hematology chronic differential hemeonc hemophagocytic hlh leukemia lymphocytic lymphohistiocytosis treatment aosd arteritis autoimmune classification gca giantcell hodgkins lymphoma
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... cells can indicate disease ... Agranulocytosis 3. ... diagnosis #workup #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
common leukemia in adults ... chemotherapy for low-risk disease ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Disease Systemic ... the chest/trunk Symptoms ... weeks or longer 3. ... AOSD #diagnosis #rheumatology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... central nervous system ... presents in young adults ... Signs and symptoms ... McDonald diagnostic criteria
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vasculitis in older adults ... sx + signs/sx of ... elicited after 2-3 ... slow taper over 1-3 ... them, but urgent rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
affects infants < 3 ... age, however the disease ... also observed in adults ... Diagnosis: HLH signs ... and symptoms can
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Symptoms (SX) in ... purpura: Strong sign ... • Progressive symptoms ... or proteinase 3 ... Differential #Diagnosis #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
history • Young adults ... ingestion • B symptoms ... in 1/3 of patients ... number of sites of disease ... #oncology #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
of the immune system ... ▪ Autoimmune diseases ... Activation Syndrome) 3. ... Presentation • Common Signs ... and Symptoms:
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... cancer-associated adult ... papules and Gottron sign ... ) • Shawl sign ... • Conduction system
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