11 results
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Diagnosis Algorithm Symptoms ... quadrant discomfort Signs ... criteria are met ... gp210/sp100) 3. ... Diagnosis #Algorithm #hepatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... affects infants < 3 ... age, however the disease ... signs and symptoms ... management #treatment #hematology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
internal organs 3 ... skin thickening Signs ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #workup
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Summary Diagnostic Criteria ... When present, symptoms ... , signs, and complications ... von Willebrand disease ... Summary #treatment #hematology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of UMN and LMN signs ... fasciculations Common Symptoms ... of UMN and LMN signs ... both UMN and LMN signs ... EMG: LMN Signs in
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
common in Asia • HLA-B51 ... skin injury) • Neurologic ... meningitis), MCC CNS symptoms ... diagnosis #management #signs ... #symptoms #rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... in 1/3 of patients ... Hodgkin Lymphoma Workup ... number of sites of disease ... classification #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... cells can indicate disease ... Agranulocytosis 3. ... #oncology #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... or proteinase 3 ... Differential #Diagnosis #Rheumatology