11 results
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Systemic inflammation ... the chest/trunk Symptoms ... weeks or longer 3. ... #AOSD #diagnosis ... #rheumatology #
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Typical symptoms ... Less Typical Symptoms ... *Chronic HFrEF may ... dysfunction 3. ... coronary artery disease
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
neurodegenerative disease ... central nervous system ... Signs and symptoms ... McDonald diagnostic criteria ... ) • Acute:
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Sweet Syndrome (Acute ... inflammatory disease ... treatment with systemic ... Sweet #Syndrome #Acute ... #Diagnosis #Hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Agranulocytosis 3. ... ’s lymphoma or acute ... workup #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
or proteinase 3 ... Eosinophilia, asthma, chronic ... Symptoms (Sx) in ... purpura: strong sign ... differential #diagnosis #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
affects infants < 3 ... Diagnosis: HLH signs ... and symptoms can ... presents as an acute ... management #treatment #hematology
Portopulmonary Hypertension
Presence of pulmonary arterial hypertension in a patient with portal hypertension
No other obvious causes (chronic
obvious causes (chronic ... Right ventricular systolic ... m/s • Other signs ... diagnosis Diagnostic criteria ... 25mmHg, PVR > 3
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Symptoms (SX) in ... purpura: Strong sign ... or proteinase 3 ... Eosinophilia, asthma, chronic ... Differential #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... • Conduction system ... muscular atrophy • Chronic