13 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
internal organs 3 ... skin thickening Signs ... and Symptoms: ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Hypothyroidism and Hyperthyroidism - Symptoms and Signs
Hypothyroidism:
 - General - From asymptomatic to myxedema coma, “Like
Hyperthyroidism - Symptoms ... and Signs Hypothyroidism ... Thinning of lateral 1/3 ... #Signs #Diagnosis ... #endocrinology
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
vomiting • Fatigue Signs ... Reduced libido • Signs ... Serum cortisol < 3 ... addisons #disease #endocrinology ... #diagnosis #signs
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
caucasian • Symptoms ... visual loss (avg. 3/ ... Unilateral • Signs ... (MP) 1 g/d for 3- ... Management #treatment #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Lung involvement 3% ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Insulin + KCI. 3) ... Signs/Symptoms/Complications ... pathophysiology #endocrinology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... elicited after 2-3 ... slow taper over 1-3 ... them, but urgent rheumatology ... GCA #Temporal #Signs
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
affects infants < 3 ... Diagnosis: HLH signs ... and symptoms can ... management #treatment #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Agranulocytosis 3. ... workup #oncology #hematology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
disturbance, psychosis 3) ... ACTH levels 3) ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology