51 results
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Sickle-cell disease ... Crises can be precipitated ... precursors). 3) ... #Features #Signs ... #Symptoms
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... internal organs 3 ... skin thickening Signs ... and Symptoms: ... rheumatology #diagnosis #signs
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
vomiting • Fatigue Signs ... Cortisol Deficiency: Signs ... Reduced libido • Signs ... #endocrinology ... #diagnosis #signs
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Guidelines for Crises ... • Sepsis (→ 3- ... (late sign) (→ ... Guidelines for crises ... Checklist #Diagnosis #Management
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases ... Clinical Signs ... years - May have signs ... CMC_IM #Potts #Disease
Whipple Disease (Tropheryma whipplei) - Diagnosis and Management 

Caused by: Tropheryma whipplei

Symptoms and Signs:
1. Migratory poly/oligoarthralgia
Whipple Disease ... Caused by: ... Tropheryma whipplei Symptoms ... and Signs: 1. ... Weight loss (90%) 3.
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... dermis Clinical Signs ... /Symptoms/Exam findings ... phase: tense 1-3 ... - Erosions and crusts
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... • Salt wasting crisis ... "salt wasting crisis ... Signs/Symptoms/Complications ... pathophysiology #genetics #endocrinology
Causes of Peripheral and Central Vertigo
PERIPHERAL VERTIGO
1. Benign paroxysmal positional vertigo (BPPV) - Short-lived (typically less
Causes of Peripheral ... fifth decades. 3. ... Méniére's disease ... weeks to months. 3. ... varying neurologic signs