58 results
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... after 2 years of treatment
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
glucocorticoid treatment ... organ-specific signs ... or symptoms (eg ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
loss of smile 3. ... life-threatening Differential ... myasthenia Diagnosis ... test - Cogan sign ... - Peek sign
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
Pathogenesis and Clinical ... spontaneous within 3- ... sensory • Before diagnosis ... pathophysiology #differential ... #diagnosis #signs
Problem Representation

An evolving summary of a patient’s clinical presentation that strives to identify 
(1) Clinical syndrome
of a patient’s clinical ... identify (1) Clinical ... syndrome (signs ... /symptoms), (2) ... demographics), and (3)
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... affects infants < 3 ... : HLH signs and ... #hematology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Diagnosis Portal ... >10 mmHg - clinically ... significant portal HTN Signs ... obstruction) • Lack of signs ... #hepatology
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Wernicke-Korsakoff syndrome ... Vitamins #Deficiency #differential ... #diagnosis #signs ... #symptoms #nutrition