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diagnosis management rheumatology differential treatment gca aion anteriorischemicopticneuropathy arteritis behcet chronic cll cord disease disorders giantcell giantcellarteritis headache hemophagocytic hlh
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
• Meningeal signs ... ) • Systemic symptoms ... and signs (e.g. ... arteritis • Acute ... #neurology #PHANTOMS
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
Definition: acute ... Doppler US : halo sign ... GiantCellArteritis #GCA #Rheumatology ... #Ophthalmology ... #Diagnosis #Algorithm
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
caucasian • Symptoms ... visual loss (avg. 3/ ... orbital pain, (Sub)acute ... Unilateral • Signs ... #ophthalmology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... meningitis), MCC CNS symptoms ... inhibitors • Uveitis- Ophthalmology ... diagnosis #management #signs ... #symptoms #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... affects infants < 3 ... Diagnosis: HLH signs ... and symptoms can ... presents as an acute
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Agranulocytosis 3. ... ’s lymphoma or acute ... workup #oncology #hematology
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
and signs below ... , Aspergillus 3. ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology ... differential #algorithm
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... elicited after 2-3 ... required +/- prompt ophthalmology ... GCA #Temporal #Signs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... affects the skin, neurologic ... • Progressive symptoms ... or proteinase 3
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