11 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... internal organs 3 ... and Symptoms: ... ), PAH (pulmonary ... #diagnosis #signs
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Hematologic malignancy ... 3. ... gastrointestinal symptoms ... • Clinical (Symptoms ... differential #diagnosis #infectiousdiseases
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Lung involvement 3% ... Other auto-immune, Infectious ... diseases, Hematological ... autoantibodies #signs ... #symptoms #mimickers
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... Connective tissue diseases ... Digital clubbing (2-3% ... Nasal polyps and signs ... , in advanced disease
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
affects infants < 3 ... age, however the disease ... Diagnosis: HLH signs ... and symptoms can ... management #treatment #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
to exclude are infections ... Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... or proteinase 3
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
or proteinase 3 ... to exclude are infections ... Presentation - Systemic Symptoms ... purpura: strong sign ... are proteinase 3
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... weeks without infection ... Physical Exam/Signs ... cells can indicate disease ... Agranulocytosis 3.
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... Pneumonia: • 3 ... • CT: Halo sign ... Constitutional symptoms ... #HIV #AIDS #pulmonary
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
3) Abdominal, ... extrapulmonary disease ... or meningitic disease ... 40% Invasive Disease ... ) #Mycoses #InfectiousDiseases