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diagnosis differential hematology management signs systemic vasculitis workup aids autoantibodies autoimmune bronchiectasis chronic classification cll erythematosus fungal hemophagocytic hiv hlh
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune disease ... internal organs 3 ... and Symptoms: ... ), PAH (pulmonary ... Scleroderma #SSc #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Lung involvement 3% ... Other auto-immune, Infectious ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Illnesses: • Pulmonary ... Hematologic malignancy 3. ... gastrointestinal symptoms ... • Clinical (Symptoms ... differential #diagnosis #infectiousdiseases
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
inflammation Symptoms ... Connective tissue diseases ... Digital clubbing (2-3% ... Nasal polyps and signs ... , in advanced disease
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
affects infants < 3 ... age, however the disease ... Diagnosis: HLH signs ... and symptoms can ... mimic common infections
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... or proteinase 3 ... Differential #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
or proteinase 3 ... to exclude are infections ... Presentation - Systemic Symptoms ... purpura: strong sign ... differential #diagnosis #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... weeks without infection ... Physical Exam/Signs ... cells can indicate disease ... Agranulocytosis 3.
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Pneumonia: • 3 ... • CT: Halo sign ... Constitutional symptoms ... #HIV #AIDS #pulmonary
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... 3) Abdominal, ... extrapulmonary disease ... or meningitic disease ... ) #Mycoses #InfectiousDiseases
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