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diagnosis differential rheumatology nephrology urine ana anca antibodies antibody antineutrophil antinuclear blood causes classification diseases hematuria key management prs pulmonary
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
Atlas of Urine Microscopy ... fresh at time of microscopy ... Leukocytes - Up to 3 ... field = normal; >3 ... #Atlas #key #diagnosis
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
• Hematuria: 3 ... urine sediment Microscopic ... urine sediment by microscopy ... hematuria: - RBC casts ... Diagnostic of GN or vasculitis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Anti-dsDNA (in 70% of cases ... Anti-Sm (Smith) 3. ... • Sjögren syndrome ... : • Microscopic ... vasculitis - MPO
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... or proteinase 3 ... PR3-ANCA): • Microscopic ... Dx: GPA, EGPA, microscopic ... are proteinase 3
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... polyangiitis), MPA (microscopic ... palpable purpura 2/2 vasculitis ... FINDINGS: • U/A: microscopic ... hematuria, RBC casts
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... or proteinase 3 ... (PR3-ANCA)): Microscopic ... • Behcet syndrome ... • Cogan syndrome
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