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diagnosis differential rheumatology antibody antineutrophil antinuclear bloodsmear borrelia classification clinical diseases fever infectiousdiseases pathology polychondritis prs pulmonary recurrentis relapsing syndromes
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... Anti-dsDNA (in 70% of cases ... • Sjögren syndrome ... Vasculitis: • Microscopic ... Jcortesizaguirr #ANA
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Summary Autoimmune ... ANCA vasculitis ... EGPA) • Auto-antibodies ... : ANCA antibody, ... hematuria, RBC casts
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
renal abnormalities ... ): • Microscopic ... LFT • ESR • ANA ... Dx: GPA, EGPA, microscopic ... ) pattern: antibodies
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
resolved after 2-3d ... Several cases have ... Syndrome: 3d of ... convalescent antibodies ... recurrentis #BloodSmear #microscopy
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
renal dysfunction ... falciparum: Most cases ... during the U.S. summer ... renal function ... dipstick test, microscopic
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
diseases 30% of cases ... Heart failure • Renal ... Anti-Matrilin-1 Ab ○ Antibodies ... Nonspecific ↑ ESR, CRP, ANA ... rheumatology #diagnosis #management
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