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diagnosis rheumatology anca antibody antineutrophil bloodsmear borrelia clinical differential diseases pathology polychondritis prs pulmonary recurrentis relapsing sjogrens syndromes
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... Anti-dsDNA (in 70% of cases ... seen in 30—70% of cases ... • Sjögren syndrome ... Vasculitis: • Microscopic
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis), MPA (microscopic ... EGPA) • Auto-antibodies ... hematuria, RBC casts ... #diagnosis #management ... #treatment
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
resolved after 2-3d ... Several cases have ... Syndrome: 3d of ... convalescent antibodies ... recurrentis #BloodSmear #microscopy
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
ab • RF • Antinuclear ... cirrhosis: 3%-20% Renal ... Distal (Type I) renal ... Adenocarcinoma Treatment ... Rheumatology #Diagnosis #Management
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
diseases 30% of cases ... Heart failure • Renal ... Anti-Matrilin-1 Ab ○ Antibodies ... affected tissue Treatment ... rheumatology #diagnosis #management
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