10 results
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
urine • 1ml blood ... urine sediment Microscopic ... urine sediment by microscopy ... hematuria: - RBC casts ... #urine #blood
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
disease Red blood ... Glomerulonephritis White blood ... tubulointerstitial nephritis, renal ... Fatty - Nephrotic syndrome ... #Differential #Microscopy
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Anti-dsDNA (in 70% of cases ... seen in 30—70% of cases ... • Sjögren syndrome ... Vasculitis: • Microscopic ... antibodies #diagnosis #rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age • 22 and 45 cases ... abnormal under the microscope ... abnormal under a microscope ... abnormal under the microscope ... #diagnosis #hematology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... polyangiitis), MPA (microscopic ... reveals increasing blood ... FINDINGS: • U/A: microscopic ... hematuria, RBC casts
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Polyarteritis nodosa • Microscopic ... • Goodpasture syndrome ... vasculitis (inflamed blood ... rash #diagnosis #rheumatology
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
resolved after 2-3d ... Northeast Africa with cases ... Several cases have ... Syndrome: 3d of ... recurrentis #BloodSmear #microscopy
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pulmonary and renal ... PR3-ANCA): • Microscopic ... Large Vessel: Blood ... Dx: GPA, EGPA, microscopic ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulmonary and renal ... pulses, bruits, or blood ... (PR3-ANCA)): Microscopic ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology
Fever After International Travel

Infectious Disease:
• Endemic in either the destination or home region

Viral Syndromes:
Arboviral infections, a
thrombocytopenia, and renal ... falciparum: Most cases ... tests of liver and renal ... function • Blood ... dipstick test, microscopic