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diagnosis differential hematology oncology syndromes ana anca antibodies antibody antineutrophil antinuclear blood causes classification cutaneous dermatologic diseases gpa granulomatosis hematuria
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
urine sediment Microscopic ... urine sediment by microscopy ... pain hematuria syndrome ... hematuria: - RBC casts ... Diagnostic of GN or vasculitis
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Vasculitis Involving ... Associated: - Microscopic ... Disease • Cogan syndrome ... #skin #dermatology ... #rheumatology #
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Anti-dsDNA (in 70% of cases ... • Sjögren syndrome ... : • Microscopic ... vasculitis - MPO ... antibodies #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... PR3-ANCA): • Microscopic ... Dx: GPA, EGPA, microscopic ... • Urinalysis (Renal ... differential #diagnosis #rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... polyangiitis), MPA (microscopic ... palpable purpura 2/2 vasculitis ... FINDINGS: • U/A: microscopic ... hematuria, RBC casts
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Polyarteritis nodosa • Microscopic ... • Goodpasture syndrome ... #Dermatologic ... rash #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
cryocrystalglobulin GN -C3 GN • Cast ... Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular Vasculitis ... vascular beds-renal ... Paraproteinemias #Hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... (PR3-ANCA)): Microscopic ... • Behcet syndrome ... • Cogan syndrome ... Differential #Diagnosis #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age • 22 and 45 cases ... abnormal under the microscope ... abnormal under a microscope ... abnormal under the microscope ... #diagnosis #hematology
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