22 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... cells: Sickle cell ... #Smear #Analysis ... #hematology #microscopy
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
smear or on bone ... develop leukostasis syndrome ... • Peripheral smear ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... and laboratory diagnosis ... non-specific red cell ... #Pathology #Smear ... #Microscopy
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... abnormal under a microscope ... smear • Bone marrow ... #diagnosis #hematology ... #oncology
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
Pathologic Red Blood ... , Sickle cell, ... Morphologies #Key #Atlas #Microscopy ... #Pathology #Hematology ... #Diagnosis #Dyspmorphic
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Diagnosis: • ... • Peripheral smear ... Lymphocytosis: Absolute blood ... #workup #oncology ... #hematology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... urine • 1ml blood ... urine sediment Microscopic ... necrosis (Sickle cell ... #renal #urine #blood
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
disease Red blood ... White blood cell ... Fatty - Nephrotic syndrome ... #Differential #Microscopy ... #Diagnosis #Nephrology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell ... - Peripheral Blood ... Smear ↑ abnormal ... #hematology
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
She was diagnosed ... and started on all-trans ... her peripheral blood ... Path #BloodSmear #Blood ... #Smear #Microscopy