21 results
Small Vessel Vasculitides
 • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Small Vessel Vasculitides ... destructive sinusitis, pulmonary ... retroorbital mass) • Microscopic ... and Sjogren's syndrome ... • IgA vasculitis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... ANCA-positive vasculitis ... polyangiitis, Microscopic ... ANCA-negative vasculitis ... IgA-associated vasculitis
Causes of Hemoptysis - Differential Diagnosis Algorithm
Massive Hemoptysis (>I00 mL in 24 hours)
 • Malignancy
 •
Vasculitis Infection ... Vasculitis • ... Goodpasture's Syndrome ... polyangiitis / microscopic ... Vascular • Pulmonary
Acanthocyte on Urine Microscopy

3D view of acanthocyte in a patient with hydralazine-induced vasculitis

Dr. Muner Mohamed @MunerMohamed1

#Acanthocyte
Acanthocyte on Urine Microscopy ... 3D view of acanthocyte ... hydralazine-induced vasculitis ... Acanthocyte #Urine #Microscopy
Classification of Vasculitis 
Vasculitis of large vessels 
 - Arteritis temporalis (giant-cell arteritis) 
 - Takayasu
granulomatosis - microscopic ... Churg-Strauss syndrome ... - Goodpasture syndrome ... - Schnitzler syndrome ... - Sjögren syndrome
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
progressing GN • New pulmonary ... PR3-ANCA): • Microscopic ... : • Behçet Syndrome ... • Cogan Syndrome ... Dx: GPA, EGPA, microscopic
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
urine sediment Microscopic ... urine sediment by microscopy ... pain hematuria syndrome ... pain + gross or microscopic ... Diagnostic of GN or vasculitis
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Vasculitis Involving ... 50% Cutaneous Vasculitis ... Leukocytoclastic Vasculitis ... Associated: - Microscopic ... Disease • Cogan syndrome
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... Autoimmune ANCA vasculitis ... polyangiitis), MPA (microscopic ... palpable purpura 2/2 vasculitis ... FINDINGS: • U/A: microscopic
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
La) - Sjogren's syndrome ... disease c-ANCA - Vasculitis ... granulomatosis p-ANCA - Vasculitis ... Microscopic polyangiitis ... Goodpasture's syndrome