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diagnosis deficiency causes differential hematology iron management oncology symptoms cll copper erythematosus gca giantcell gravis leukemia lupus lymphocytic mds myasthenia
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Pregnancy, EPO treatment ... Elite athletes • Chronic ... Loss (without anaemia ... ): GI cancers, Donations ... diagnosis #causes #nutrition
Risk Factors and Signs of Copper Deficiency Risk Factors: • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Risk Factors and Signs ... bowel disease, Chronic ... dental fixatives, Treatment ... , Malnutrition Signs ... Haematological: Anaemia
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
pylori, Celiac, Enteritis ... : Gl lesions / cancer ... Inflammation: IBD, Chronic ... differential #diagnosis #anemia ... #nutrition
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... systemic complaints- anemia ... of the steroid treatment ... Treatment of GCA ... GCA #Temporal #Signs
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
syndrome, rheumatoid arthritis ... distribution in the 30s ... test - Cogan sign ... - Peek sign ... inhibition - Chronic
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... Platelet Disorders • Nutritional ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Leukemia - Summary Cancer ... Physical Exam/Signs ... • Neutropenia, anemia ... microglobulin Treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
lymphopenia, low PLT • Anemia ... (C3 and C4) • ds-DNA ... with Lupus: • Chronic ... leukemia • Lung cancer ... • Cervical cancer
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