8 results
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Induced Muscle Toxicity ... Atorvastatin Diagnosis ... Statin #muscle #toxicity ... #myopathy #diagnosis ... #management #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... 48% depending on the ... : >3 symptoms, or ... #management #hematology ... #oncology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
factor PRES Diagnosis ... Neurological symptoms ... Differential Diagnosis ... Medication/Drug toxicity ... #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
that diminish the ... symptoms that may ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... Pulmonary Renal Syndromes ... o infection • Echocardiogram ... or serologies + symptoms ... #management #treatment
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
respiratory distress syndrome ... gradually with symptoms ... macrophages in the ... Improvement in symptoms ... #management #Toxicology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... Confusion, visual symptoms ... Drug reaction/ART toxicity ... #Inflammatory #Syndrome ... #Management
Management of Immune Checkpoint Inhibitor (ICI) Induced Cardiotoxicity
Problem - Immune checkpoint inhibitors (ICIs) are associated with
normal, significant echocardiogram ... : G1 toxicity: ... worsening G2-G3 toxicity ... 4-6 weeks G4 toxicity ... Cardiotoxicity #cardiology #oncology