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differential neurology hematology pulmonary oncology pathophysiology rheumatology algorithm clinical criticalcare disease hemophagocytic hlh icu lymphohistiocytosis sclerosis toxicity toxicology workup acquired
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
less systemic symptoms ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... after 2 years of treatment
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
and Management ... Summary Diagnostic ... , signs, and complications ... of symptoms and ... #Management #Summary
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
What is a Boxer’s fracture?? Fracture of the 4th or 5th metacarpal neck - Common in
hand Symptoms/ ... – compartment syndrome ... Overlying wounds or signs ... recommended if injury ... Hand #Metacarpal #Diagnosis
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
progression: over 1-3d ... ophthalmoplegia), systemic signs ... Imaging (if atypical symptoms ... prevent corneal injury ... #Management #Treatment
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Direct muscle injury ... Risk of muscle injury ... Atorvastatin Diagnosis ... toxicity #myopathy #diagnosis ... #management #treatment
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
myasthenia Diagnosis ... test - Cogan sign ... - Peek sign ... Myasthenia #Gravis #diagnosis ... #management #neurology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
to local skin injury ... meningitis), MCC CNS symptoms ... Arthritis, AS Treatment ... #diagnosis #management ... #signs #symptoms
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... symptoms can mimic ... • Bicytopenia Treatment ... #management #treatment
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