16 results
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
pathogenesis and clinical ... pyrophosphatase activity ... - CPPD Crystals ... Signs #Symptoms #Pathophysiology ... #Diagnosis
The interferon (IFN) signature: what’s the point? How to use it in clinical practice?

Characterizing activity of
Characterizing activity ... clinic allows: ... understanding of pathophysiology ... IFN #signature #diagnosis ... #management
Intraoperative Massive Blood Loss - Guidelines for Crises in Anaesthesia
Expected or unexpected major haemorrhage

❶ Call for
problem and note the ... plan between surgical ... an appropriate clinical ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... activity of the ... anaerobic metabolism Diagnosis ... presentation - Clinical ... #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... characteristic features Clinical ... Tuberculosis Diagnosis ... assay (IGRA) • PPD ... #Management #Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... characteristic features Clinical ... Tuberculosis Diagnosis ... assay (IGRA) • PPD ... #Management #Treatment
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
) Pathophysiology ... deposit and can activate ... culture used to diagnose ... #Rheumatology #diagnosis ... #management
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
clinical examination ... lateral sclerosis Pathophysiology ... Excessive glutamate activity ... by decreasing activity ... #management
Intraoperative Bronchospasm - Guidelines for Crises in Anaesthesia

❶ Call for help and inform theatre team of
Other drugs at clinician ... Obtain a chest X-ray ... as soon as clinically ... safe to do so. ⓮ Plan ... #Management #Workup
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
and Management ... Person Syndrome Pathophysiology ... Clinical Manifestations ... continuous motor unit activity ... #Management #treatment