The interferon (IFN) signature: what’s the point? How to use it in clinical practice? Characterizing activity of IFN pathway in the clinic allows: - Better understanding of pathophysiology - To propose new classifications for diseases - To propose new targeted therapies - Better stratification of patients Limitations of the IFN score: - Semiquantitative analysis - Dynamic/variable responses and indirect measurements - Costly for clinical practice +++ By Dr. Nader Yatim via Dr. Benjamin Terrier @TerrierBen #interferon #IFN #signature #diagnosis #management