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Serotonin receptors and sites of actions.

#Serotonin #Receptors #Sites #Actions #5HT #Pharmacology

Sites #Actions #5HT

Hyperthermic Toxidromes
Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures.
• Sympathomimetic -

(epi, NE, DA, 5HT ... Excessive release of 5HT

Drugs for Depression and Anxiety Disorders

Selective Serotonin Reuptake Inhibitors
• Citalopram, Escitalopram, Fluoxetine, Fluvoxamine, Paroxetine, Sertraline,

prevent NE, DA, and 5HT

Functional Dyspepsia Management Options - Efficacy
- Proton pump inhibitors
- H. Pylori treatment
- Metoclopramide

behavioral - 5HT4

Cephalosporins - Table of Coverage by Generation

1st Generation Cefazolin, cephalexin
2nd Generation Cefotetan
3rd

Generation Cefepime 5th

Cephalosporin Antibiotic Generations - Mnemonic
1st Generation "FA/PHA": CEFAZOLIN, CEFADROXIL, CEPHALEXIN, CEPHALOTHIN, CEPHAPIRIN, CEPHRADINE
2nd Generation "Everything Else":

CEFEPIME, CEFPIROME 5th

Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
-> Increased Testosterone -> Testosterone metabolized into DHT by type

metabolized into DHT ... in prostate -> DHT ... testosterone into DHT ... cells -> Decr DHT

Cephalosporin Comparison - Coverage
1st Generation Cefazolin, Cephalexin
2nd Generation Cefaclor, Cefotetan, Cefoxitin, Cefuroxime
3rd Generation

Ceftaroline: "5th ... be called the 5th

Cephalosporin Coverage by Generation - HENPECKS Mnemonic
1st Gen: PEK (Proteus, E. coli, Klebsiella)
2nd Gen: HNPEK (Add

Streptococcus and MSSA) 5th

$Boxer's Fracture - Hand X-Ray Diagnosis: Fracture of the neck of the 5th metacarpal Boxer's fracture is a$

the neck of the 5th ... most commonly the 5th

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