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hematology diagnosis differential oncology causes auer auerrods blood bloodsmear cancer chronic clinical cll disorders gap globulin lymphocytic mds microscopy myelodysplasia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
: ALL, CML, AML, ... - infiltrates (anemia ... , thrombocytopenia ... cutaneous plaques) AML ... #Hematology #Oncology
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... 6.8 g/dL), and thrombocytopenia ... bilobed nuclei, fine ... (APL) following ... (AML) t(8;21),
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 Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... SLE • CLL • APLA ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... changes), high MCV anemia ... not required in all ... Diagnosis #Causes #Workup ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... , thrombocytopenia ... Transform to DLBCL, PML ... #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... involve one, two, or all ... transformation to AML ... Workup: • Complete ... progression to AML
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... • Plasma cell leukemia ... Castleman disease • AL ... : Lymphoma, Leukemia ... Thalassemia, Sickle cell anemia
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
acute myeloid leukemia ... (AML). ... cytopenias and AML ... disease tolerate anemia ... #algorithm #hematology
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