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Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... Pathophysiology • DDx: AA ... Expectation • Rx Algorithm ... @ZhuoerXie #Aplastic
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia Fanconi Anemia Acquired Aplastic Anemia Dyskeratosis Congenita & Telemore Biology
Aplastic Anemia ... Anemia Acquired Aplastic ... BoneMarrow #Failure #Aplastic
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Differential Diagnosis Algorithm ... • Toxins • Aplastic ... Differential #Diagnosis #Algorithm
Hypoxemia Differential Diagnosis Algorithm by A-a Gradient Normal A-a Gradient: • ↓ Atmospheric pressure • Hypoventilation: CNS
Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #pulmonary #Aa
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Differential Diagnosis Algorithm ... Megakaryopoiesis • Aplastic ... Differential #Diagnosis #Algorithm
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Non-hemolytic: ACD, Aplastic ... #Anemia #MCV #Algorithm
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... mutations) • Immune Aplastic ... HIV • Immune Aplastic ... consistent with aplastic
Amyloidosis Types - Comparison Table Proteins depositing where they shouldn't • AL • TTR • AA Julia Gips,
AL • TTR • AA
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Differential Diagnosis Algorithm ... FISH • Acquired Aplastic ... Differential #Diagnosis #Algorithm
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Deficiency • Aplastic ... Differential #Diagnosis #Algorithm
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