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management differential hematology myositis vasculitis ana antibodies antinuclear arthritis behcet classification disease erythematosus hemeonc hemophagocytic henochscholeinpurpura hlh hsp iga leukostasis
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... less systemic symptoms ... , holster sign, ... anti-synthetase syndrome ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... context of other symptoms ... SLE), Sjogren's Syndrome ... #patterns #rheumatology ... #diagnosis #differential
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... WBC >100k, + lab signs ... of end organ damage ... #TLS #diagnosis ... #management #hematology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Sclerosis (MS) is an autoimmune-mediated ... • Or brainstem syndromes ... Multiple Sclerosis Diagnosis ... Signs and symptoms ... lesions) McDonald diagnostic
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
polymorphisms alter ... by neutrophilic autoimmune ... nephrotic/nephritic syndrome ... Pathophysiology #Diagnosis ... #Signs #Symptoms
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... ) Differential Diagnosis ... Glucocorticoids 5-ASA ... #signs #symptoms ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... disease • Non-autoimmune ... rheumatologic diseases ... Induced Lupus: • Symptoms ... #Rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis - Signs ... and Symptoms • ... Thrombocytosis, Felty's syndrome ... #Symptoms #diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... Presentation - Systemic Symptoms ... purpura: strong sign ... LFT • ESR • ANA ... #rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... Myositis #Myopathy #rheumatology
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