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Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
gastrointestinal, and/or central ... nervous system ... purpura: strong sign ... LFT • ESR • ANA ... #rheumatology #classification
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Systemic Lupus (SLE) General ... Butterfly rash, Vasculitis ... in small joints Nervous ... haemolytic Coombs positive ... erythematosus #signs
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
vasculitis) • ... also involved), Venous ... Skin lesions • Positive ... Glucocorticoids 5-ASA ... diagnosis #management #signs
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... , and elevated serum ... APLA/LAC: • Renal ... artery or vein ... thrombosis • Pelvic vein