Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin (85%): Photosensitivity, Butterfly rash, Vasculitis, Purpura, Urticaria Chest (50%): Pleurisy / effusion, Restrictive lung defect (rare) Raynaud's phenomenon (20%) Joints (90%): Aseptic necrosis of hip (rare), Arthritis in small joints Nervous system (60%): Fits, Hemiplegia, Ataxia, Polyneuropathy, Cranial nerve lesions, Psychosis, Demyelinating syndromes Heart (25%): Pericarditis, Endocarditis, Aortic valve lesions Abdominal pain (20%) Renal disease (30%): Glomerulonephritis Myositis(5%) Blood (75%): Anemia (normochromic nomocytic or haemolytic Coombs positive), Leucopenia/lymphopenia, Thrombocytopenia #Lupus #SLE #systemic #erythematosus #signs #symptoms #diagnosis #rheumatology
