7 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... in small joints Nervous ... disease (30%): ... haemolytic Coombs positive ... erythematosus #signs
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... also involved), Venous ... Skin lesions • Positive ... Glucocorticoids 5-ASA ... diagnosis #management #signs
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pulmonary and renal ... gastrointestinal, and/or central ... nervous system ... purpura: strong sign ... LFT • ESR • ANA
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... , and elevated serum ... APLA/LAC: • Renal ... artery or vein ... thrombosis • Pelvic vein
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulmonary and renal ... purpura: Strong sign ... Angiitis of the Central ... Nervous System: ... nervous system
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
the lungs and regional ... granulomas with central ... Lymph nodes • Central ... nervous system ... Acid-fast staining, NAA
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
the lungs and regional ... granulomas with central ... Lymph nodes • Central ... nervous system ... Acid-fast staining, NAA