16 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
mutations) • Immune ... Aplastic Anemia Clinical ... HCV - HIV • Immune ... oncology #hematology #diagnosis ... #management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Progression: (+) Immune ... rest LTBI (-) Immune ... characteristic features Clinical ... Tuberculosis Diagnosis ... #Management #Treatment
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... Atorvastatin Diagnosis ... IU/I • SAMS clinical ... increased spontaneous activity ... #management #treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Progression: (+) Immune ... rest LTBI (-) Immune ... characteristic features Clinical ... Tuberculosis Diagnosis ... #Management #Treatment
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... increased B-cell activity ... → local immune ... renal failure Clinical ... anterior/posterior MSK
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Association with disease activity ... -15% If SLE is clinically ... SLE-SSc-AlM overlap syndromes ... association with auto-immune ... erythematosus #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... underlying genetic immune ... absent NK cell activity ... #management #treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... context of primary immune ... Clinical Features ... Erythematosus #Diagnosis
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of the clinical ... Excessive glutamate activity ... are the immune ... by decreasing activity ... #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Erythema nodosum • Immune ... • PET scan - activity ... lymph node biopsy (diagnostic ... hematology #oncology #management