13 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... ACLF) Clinical Guidelines ... Hepatitis (AAH) Drug-Induced ... Failure #Cirrhosis #Hepatology ... #diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Algorithm DILI ... toxic aetiology: Skin ... dechallenge • Acute ... #Algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... acid metabolism products ... headache, malaise) → Acute ... ) Differential Diagnosis ... #Pregnancy #hepatology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... Blood products contain ... infections with skin ... #diagnosis #management ... #hematology #reactions
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
of fibrin split products ... which can plug blood ... : • + Clinical ... syndrome • Warfarin-induced ... hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
eruptions, diarrhea, liver ... Blood products contain ... infections with skin ... #diagnosis #management ... #hematology #reactions
Esophageal Variceal Bleeding - Scoping Summary
GENERAL PRINCIPLES OF MANAGEMENT (VARICEAL-B):
V - Vasoconstrictor therapy: (Octreotide 50mcg bolus
TEG -> dec. in blood ... products E - ... not initiate in acute ... Summary #Endoscopy #diagnosis ... #management #algorithm
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Sepsis • Drug-induced ... thrombocytopenia • Liver ... Fibrin degradation products ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... ABO incompatible blood ... organ damage Clinical ... DIC • Severe Liver ... #hematology
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
stores in the liver ... to produce Acetoacetic ... Insulin and Ketoacid-induced ... #diagnosis #differential ... #algorithm #management