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rheumatology hepatology treatment aclf activation anemia aplastic blood causes chronic cirrhosis coagulation dermatology dic differential dili disseminated druginduced erythematosus failure
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... ACLF) Clinical Guidelines ... Hepatitis (AAH) Drug-Induced ... Failure #Cirrhosis #Hepatology ... #diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Algorithm DILI ... toxic aetiology: Skin ... dechallenge • Acute ... #Algorithm #hepatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... Causes: - Drug induced ... deficiency • Liver ... - APLS • Acute ... #hematology #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Sepsis • Drug-induced ... thrombocytopenia • Liver ... #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... presents as an acute ... lymph node, or liver ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... 3rd Decade Skin ... Classification: • Acute ... Differential Diagnosis ... Clinical Features
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... renal failure Clinical ... nodes: 13-15%, skin ... heart (2-5%), liver ... #Management #Signs
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... Headaches • Pale skin ... cells is much reduced ... Anemia #oncology #hematology ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... organ damage Clinical ... DIC • Severe Liver ... #Coagulation #diagnosis ... #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... salivary ducts Clinical ... vasculitis: 10%-16% Liver ... Nephrogenic DI Hematologic ... Diagnosis #Management
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