9 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Syndrome • Secondary ... Hypereosinophilic Syndrome • Clinically ... disorders • Diagnosis ... and Treatment Algorithm ... Syndrome #HES #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... leakage of RBC's secondary ... deficiency • Liver ... #hematology #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Screen for secondary ... glucocorticoid treatment ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... Arthralgia/arthritis, Skin ... Muscular: normal CK ... #management #treatment ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... #Management #Hematology ... #Rheumatology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
GrepMed Handbook Clinical ... , hair growth, skin ... Acromegaly occurs secondary ... GH stimulates liver ... Endocrinology #Treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... salivary ducts Clinical ... vasculitis: 10%-16% Liver ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Management of Pruritus in Patients with Chronic Kidney Disease
Pruritus with no primary lesions - differential diagnosis:
- differential diagnosis ... pruritus • Liver ... pruritus • Hematologic ... #Pruritus #Treatment ... #Algorithm #Hemodialysis
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
auricular papules Clinical ... without increasing CK ... positive patients Treatment ... Dermatomyositis #diagnosis ... #management #rheumatology