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rheumatology management differential druginduced syndrome activation approach arthropathies arthropathy comparison disease disorders erythematosus gout laboratory macrophage mas monoarthritis monoarticular pain
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- Differential Diagnosis ... Algorithm Monoarthritis ... with Systemic Lupus ... Erythematosus (SLE ... #Disorders #msk
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Lupus (DIL): ... Constitutional symptoms, Arthritis ... , SCLE-DIL (terbinafine ... • Immunologic Workup ... #diagnosis #management
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... spondyloarthropathies, lupus ... Chronic = RA, SLE ... #Joint #Pain #MSK ... approach #workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... versus DIL • ... • Immunologic Workup ... life-threatening • Treatment ... Erythematosus #Diagnosis
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Constitutional symptoms, Arthritis ... , SCLE-DIL (terbinafine ... • Immunologic Workup ... #DIL #rheumatology ... #diagnosis #treatment
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... • Systemic lupus ... (to support a diagnosis ... #laboratory #workup ... #diagnosis #testing
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
SJIA], systemic lupus ... erythematosus [SLE ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Algorithm Polycythemia ... Better call hematology ... some time, let’s see ... #Algorithm #workup ... #hematology
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
deposition in joints ... attacks • Other joints ... frequent attacks • Arthritis ... Dual-energy CT → MSU ... #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Hematologic: ... phenomenon (16%) MSK ... Arthralgia and Arthritis ... Adenocarcinoma Treatment
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