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differential hepatology injury dermatology pruritus secondary systemic disorders drug druginduced gastroenterology hepatitis idiosyncratic induced liverenzymes management platelet primary thrombocytopenia
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... disease 6-9 mo ... gastroenterology #algorithm ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... Algorithm DILI ... for alternative causes ... disease, Hepatic ... #Algorithm #hepatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Pruritus - Generalized ... Algorithm - Systemic ... and Primary Causes ... #Diagnosis #Algorithm ... #causes
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... gastric bypass), LFT ... (liver disease) ... #Causes #Workup
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... Causes of Acute ... • Iatrogenic: DILI ... #algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Algorithm Severe ... • Cholestatic disease ... • Others #LFTs ... #Algorithm #Causes
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
- Differential Diagnosis ... Algorithm Blood ... secondary #systemic #generalized ... #Diagnosis #Algorithm ... #causes
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