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differential hepatology injury dermatology gastroenterology generalized pruritus secondary systemic alkaline alp ascites biliary calling cholangitis cirrhosis consultation disorders drug druginduced
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... disease 6-9 mo ... gastroenterology #algorithm ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... Algorithm DILI ... for alternative causes ... disease, Hepatic ... #Algorithm #hepatology
The Liver Consult Primer - Guide to calling a consult HPI: - Start with reason for consult
Primer - Guide ... - Vitals - LFTs ... GTT, indirect bili ... disease work up ... Calling #Referral #Hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Workup History ... gastric bypass), LFT ... (liver disease) ... unclear, or if a primary ... #Causes #Workup
Liver Mass - Differential Diagnosis Algorithm Cystic: • Benign - Simple: Simple
Diagnosis Algorithm ... Disease, Caroli's ... Malignant - primary ... #Algorithm #Causes ... #Hepatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Algorithm - Systemic ... and Primary Causes ... • Cholestatic liver ... disease Creatinine ... #Algorithm #causes
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Algorithm Malignant ... Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... #Algorithm #Causes ... #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Algorithm Vascular ... Causes of Acute ... • Iatrogenic: DILI ... #algorithm #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Algorithm ALP ... Intestine - Other causes ... - Drugs - Primary ... #Algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Algorithm Severe ... • Cholestatic disease ... • Others #LFTs ... #Algorithm #Causes
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